L-Abrine

CAS: 526-31-8

Ref. 3D-FM52417

Product Information

• Name: L-Abrine
• Synonyms: (S)-3-(1H-Indol-3-yl)-2-methylaminopropionic acidN-Methyl-L-tryptophan, (2S)-3-(1H-Indol-3-yl)-2-(methylammonio)propanoate, (2S)-3-(1H-Indol-3-yl)-2-(methylazaniumyl)propanoate, (S)-3-(1H-Indol-3-yl)-2-methylaminopropionic acid, <span class="text-smallcaps">L</span>-(+)-Abrine, <span class="text-smallcaps">L</span>-N-Methyltryptophan, <span class="text-smallcaps">L</span>-Tryptophan, N-methyl-, Abrine, Abrine (amino acid), H-N-Me-Trp-OH, N-Methyl-<span class="text-smallcaps">L</span>-tryptophan, N-Methyltryptophan, N-α-Methyl-<span class="text-smallcaps">L</span>-tryptophan, Nplc 0233, Tryptophan, N-methyl-, <span class="text-smallcaps">L</span>-
• CAS: 526-31-8

Description

L-Abrine is a plant toxin that belongs to the group of abrinoids. It is a chiral molecule and can exist as an L-form or D-form. The L-form is used in some analytical methods, such as gas chromatography, while the D-form is used in medical purposes. L-Abrine has been shown to have anti-HIV effects by inhibiting reverse transcriptase and deoxyribonuclease activity. It has also been shown to inhibit colony stimulating factor production and decrease bacterial growth in vitro. L-Abrine inhibits the replication of bacteria by binding to adenylate cyclase and blocking the enzyme's ability to synthesize cAMP from ATP. This inhibition prevents protein synthesis, leading to cell death.

• Brand: Biosynth

Chemical properties

• Molecular weight: 218.25 g/mol
• Formula: C₁₂H₁₄N₂O₂
• Purity: Min. 95%
• Color/Form: Powder