Melicopidine

CAS: 475-91-2

Ref. 3D-FM65850

Product Information

• Name: Melicopidine
• Synonyms: 1,3-Dioxolo(4,5-b)acridin-10(5H)-one, 4,11-dimethoxy-5-methyl-, Brn 0335565, Nsc 34757

Description

Melicopidine is a natural compound with cytotoxic and anti-cancer properties. It is found in the genus Melicope, which belongs to the Rutaceae family. This plant contains many chemical compounds, including acridone, which has been shown to have anti-cancer properties. Melicopidine has been shown to inhibit the growth of human cervical cancer cells at low concentrations by blocking cell cycle progression. The mechanism of action is not yet known, but it may be due to melicopidine’s ability to bind with DNA and alter its structure or its inhibition of protein synthesis. Melicopidine has also been shown to have toxicological effects on animals at high doses, such as weight loss and erythema (redness).

• Brand: Biosynth

Chemical properties

• Molecular weight: 313.3 g/mol
• Formula: C₁₇H₁₅NO₅
• Purity: Min. 95%
• InChI: InChI=1S/C17H15NO5/c1-18-10-7-5-4-6-9(10)13(19)11-12(18)15(21-3)17-16(14(11)20-2)22-8-23-17/h4-7H,8H2,1-3H3
• InChI key: InChIKey=TZZNUDMEMFBPQI-UHFFFAOYSA-N
• SMILES: COc1c2c(c(OC)c3c1c(=O)c1ccccc1n3C)OCO2