Methyl 3-fluoro-2-thiophenecarboxylate

CAS: 100421-52-1

Ref. 3D-FM75888

Product Information

• Name: Methyl 3-fluoro-2-thiophenecarboxylate
• Synonyms: 2-Thiophenecarboxylic Acid, 3-Fluoro-, Methyl Ester, Methyl 3-fluorothiophene-2-carboxylate
• CAS: 100421-52-1

Description

Methyl 3-fluoro-2-thiophenecarboxylate is a fluorinating agent that efficiently adds fluorine to a variety of substrates in organic synthesis. The addition of the fluorine atom is usually accomplished by treating the substrate with an acidified solution of methyl 3-fluoro-2-thiophenecarboxylate and an excess of hydrogen fluoride. This agent is used for the preparation of amides, tetrafluoroborate, hydrazide, and other derivatives. Methyl 3-fluoro-2-thiophenecarboxylate can be decarboxylated to give an acid which can be saponified to produce a carboxylic acid. This reaction also produces xylenes as a byproduct. In addition, this compound can be used to couple two different molecules together using chemical reactions such as hydrolysis, decarboxylation, or coupling. Finally, methyl 3-fluoro-2-

• Brand: Biosynth

Chemical properties

• Molecular weight: 160.17 g/mol
• Formula: C₆H₅FO₂S
• Purity: Min. 95%
• InChI: InChI=1S/C6H5FO2S/c1-9-6(8)5-4(7)2-3-10-5/h2-3H,1H3
• InChI key: InChIKey=UKIUEFZYSXIGPY-UHFFFAOYSA-N
• SMILES: COC(=O)c1sccc1F