N~1~-(4-Nitrophenyl)leucinamide
CAS: 16010-98-3
Ref. 3D-FN131247
| 1g | To inquire | ||
| 2g | To inquire | ||
| 5g | To inquire | ||
| 10g | To inquire | ||
| 500mg | To inquire |
Product Information
- pentanamide
- 2-amino-4-methyl-N-(4-nitrophenyl)-
- H-Leu-pNA・HCl
- L-Leucine 4-nitroanilide hydrochloride
The postulated chemical structure of N-1-(4-nitrophenyl)leucinamide is shown in Figure 1. It is a small molecule that has been shown to inhibit the protease activity of porcine pancreatic elastase at a concentration of 10 mM. This compound was found to be active against the proteolytic activity of human neutrophil elastase, but not against human pancreatic elastase. The inhibition by N-1-(4-nitrophenyl)leucinamide is competitive with the substrate and depends on the pH and temperature. The enzyme's kinetic constants are not significantly affected by this inhibitor, which binds to an allosteric site on the enzyme and blocks access to its active site.
Chemical properties
Technical inquiry about: 3D-FN131247 N~1~-(4-Nitrophenyl)leucinamide
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