1-O-Octadecyl-2-O-methyl-rac-glycero-3-phosphocholine

CAS: 70641-51-9

Ref. 3D-FO111151

Product Information

• Name: 1-O-Octadecyl-2-O-methyl-rac-glycero-3-phosphocholine
• Synonyms: Edelfosine, ALP, ET 18-OCH3, ET-18-OMe, NSC 324368, NSC 343649, Ro 14-5243, (2R)-2-methoxy-3-(octadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate, 1-O-Octadecyl-2-O-Methyl-Sn-Glycero-3-Phosphocholine, 1-O-Octadecyl-2-O-methyl-rac-glyceryl-3-phosphorylcholine, 1-Octadecyl-2-methylglycero-3-phosphorylcholine, 2-Methoxy-3-(Octadecyloxy)Propyl 2-(Trimethylammonio)Ethyl Phosphate, 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7-methoxy-N,N,N-trimethyl-, hydroxide, inner salt, 4-oxide, (+-)-, 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7-methoxy-N,N,N-trimethyl-, inner salt, 4-oxide, Brn 4358577, Choline hydroxide, (+-)-2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate, inner salt, ET 18-OCH₃, Edelfosina, Edelfosina [INN-Spanish], Edelfosine [INN], Edelfosinum, Edelfosinum [INN-Latin], Et 18-Och3, Racemic 1-O-octadecyl-2-O-methylglycero-3-phosphocholine, Unii-1Y6Sna8L5S, rac-1-Octadecyl-2-methoxyglycero-3-phosphocholine
• CAS: 70641-51-9

Description

Edelfosine is a phospholipid that selectively binds to nuclear DNA, leading to apoptosis. It also binds to the G-protein coupled receptors and inhibits the release of Ca2+ from intracellular stores. Edelfosine has been shown to inhibit the growth of Leishmania in vitro as well as in vivo. This drug is being studied for its potential use in inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 523.73 g/mol
• Formula: C₂₇H₅₈NO₆P
• Purity: Min. 95%