H-Phe-Gly-Gly-OH

CAS: 23576-42-3

Ref. 3D-FP109288

Product Information

• Name: H-Phe-Gly-Gly-OH
• Synonyms: 10: PN: DE102007008596 SEQID: 10 unclaimed protein, 10: PN: WO2008098569 SEQID: 10 claimed protein, 136: PN: WO2007046818 PAGE: 60 claimed protein, 18: PN: WO2016105375 SEQID: 18 claimed protein, 2-[2-[(2S)-2-Amino-3-phenylpropanamido]acetamido]acetic acid, 2-[[2-[[(2S)-2-Azaniumyl-3-phenylpropanoyl]amino]acetyl]amino]acetate, <span class="text-smallcaps">L</span>-Phenylalanylglycylglycine, Glycine, <span class="text-smallcaps">L</span>-phenylalanylglycyl-, Glycine, N-(N-<span class="text-smallcaps">L</span>-phenylalanylglycyl)-, Glycine, N-[N-(3-phenyl-<span class="text-smallcaps">L</span>-alanyl)glycyl]-, L-Phenylalanylglycylglycine, Phenylalanine-glycine-glycine, Phenylalanylglycylglycine
• CAS: 23576-42-3

Description

H-Phe-Gly-Gly-OH is a phosphatase enzyme inhibitor that acts as a competitive inhibitor of serine/threonine phosphatases. It has been shown to inhibit the activity of protein data, which are enzymes that catalyze the hydrolysis of phosphate groups from proteins. This inhibition of protein data leads to an increase in the levels of protein kinase A (PKA) and cyclic AMP (cAMP) in human serum. H-Phe-Gly-Gly-OH also inhibits an enzyme called phospholipase A2, which is responsible for fatty acid metabolism, leading to an accumulation of fatty acids in cells. It has been shown that H-Phe-Gly-Gly-OH has anticancer activity against meningioma and squamous carcinoma cells in humans.

• Brand: Biosynth

Chemical properties

• Molecular weight: 279.29 g/mol
• Formula: C₁₃H₁₇N₃O₄
• Purity: Min. 95%