Product Information
Name:H-Phe-Gly-Gly-Phe-OH
Brand:Biosynth
Description:H-Phe-Gly-Gly-Phe-OH is a tetrapeptide that is synthesized by the enzyme pepsin in a high concentration. Pepsin cleaves proline from the sequence (H-Phe-Gly) and replaces it with hydroxylated phenylalanine. The peptide is soluble in 0.1 M sodium acetate, pH 5.0, but precipitates at pH 4.0 or below. It binds to sephadex G100 but not to Sepharose CL4B or Sephadex G25M, and can be denatured by heating to 100°C for 10 minutes or by exposure to metal ions such as copper(II) sulfate. H-Phe-Gly-Gly-Phe-OH has been used as an analog for the amino acid sequence Gly-Leu in order to study its effects on receptor affinity and protein stability.br>br
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Chemical properties
Molecular weight:426.47 g/mol
Formula:C22H26N4O5
Purity:Min. 95%
Technical inquiry about: H-Phe-Gly-Gly-Phe-OH
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