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Polyphemusin II-Derived Peptide
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Polyphemusin II-Derived Peptide

CAS: 229030-20-0

Ref. 3D-FP109318

1mg
1,232.00 €
2mg
2,142.00 €
100µg
270.00 €
250µg
454.00 €
500µg
757.00 €
Estimated delivery in United States, on Friday 3 May 2024

Product Information

Name:
Polyphemusin II-Derived Peptide
Synonyms:
  • H-Arg-Arg-2-Nal-Cys-Tyr-Arg-Lys-D-Lys-Pro-Tyr-Arg-Cit-Cys-Arg-OH H-RR(2-Nal)CYRK(dK)PYR(Cit)CR-OH
  • 68:PN: WO2008075370 SEQID: 69 claimed protein
  • 69: PN: WO2008075369 SEQID: 69claimed protein
  • T 140
  • T 140 (peptide)
Description:

Polyphemusin II-derived peptide H-Arg-Arg-2-Nal-Cys-Tyr-Arg-Lys-D-Lys-Pro-Tyr-Arg-Cit (PIIH) is a cyclic polypeptide with a disulfide bond. PIIH binds to the alpha4beta1 integrin receptor, which is involved in the adhesion of leukocytes to endothelial cells and the migration of monocytes and lymphocytes. PIIH has been shown to be a potent inhibitor of chemokine binding to cxcr4, an important regulator of inflammatory response in mouse tumor models. PIIH also inhibits hiv infection as it inhibits the release of virus from infected cells. This pharmacological effect is mediated by its ability to bind HIV gp120 and block gp120 binding to CD4 receptors on target cells.

Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
2,037.43 g/mol
Formula:
C90H141N33O18S2
Purity:
Min. 95%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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