PAR-2 (1-6) (human) trifluoroacetate salt
CAS: 202933-49-1
Ref. 3D-FP109441
| 10mg | 272.00 € | ||
| 25mg | 454.00 € | ||
| 50mg | 752.00 € | ||
| 100mg | 1,229.00 € | ||
| 250mg | 2,673.00 € |
Product Information
- H-Ser-Leu-Ile-Gly-Lys-Val-OH H-SLIGKV-OH
PAR-2 is a cytosolic protein that is activated by calcium. PAR-2 activation induces the synthesis of prostaglandins and other inflammatory mediators, which stimulate the release of substances from cells such as cytokines and chemokines. PAR-2 also has an important role in cell proliferation, differentiation, apoptosis, and cancer development. PAR-2 activation is induced by proteases such as trypsin or soybean trypsin inhibitor. The trifluoroacetate salt form of PAR-2 (1-6) has been used to inhibit protease activity in colon cancer cells and prostate cancer cells.
PAR-2 (1-6) (human) trifluoroacetate salt H-Ser-Leu-Ile-Gly-Lys-Val-OH trifluoroacetate salt is a potent chemical inhibitor of trypsin activity with IC50 values of 0.5 µM for soybean trypsin inhibitor
Chemical properties
Technical inquiry about: 3D-FP109441 PAR-2 (1-6) (human) trifluoroacetate salt
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