Rifamycin SV sodium

CAS: 14897-39-3

Ref. 3D-FR27730

Product Information

• Name: Rifamycin SV sodium
• Synonyms: 5,6,9,17,19,21-Hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11 (2H)-dione 21-acetate sodium salt, 2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan, rifamycin deriv., 2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione, 5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-, 21-acetate, sodium salt, Cb 01-11, Monosodium rifamycin SV, NSC 146718, Rifamycin SV Monosodium, Rifamycin SV sodium salt, Rifamycin Sodium, Rifamycin sodium salt, Rifamycin, monosodium salt, Rifamycin, sodium salt (1:1), Tuborin
• CAS: 14897-39-3

Description

Rifamycin SV sodium is a hydroxide solution of the antibiotic rifamycin. Rifamycin SV sodium inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Rifapentine also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.

• Brand: Biosynth

Chemical properties

• Molecular weight: 719.75 g/mol
• Formula: C₃₇H₄₆NNaO₁₂
• Purity: Min 900U/Mg
• Color/Form: Powder