N-Tritylimidazole

CAS: 15469-97-3

Ref. 3D-FT147363

Product Information

• Name: N-Tritylimidazole
• Synonyms: 1-(Triphenylmethyl)imidazole, 1-Triphenylmethylimidazole, 1-Tritylimidazole
• CAS: 15469-97-3

Description

N-tritylimidazole is a palladium complex that was designed as an inhibitor of glycosidases. It binds to the active site of these enzymes and inhibits their function. N-tritylimidazole has been shown to inhibit the growth of Gram-positive bacteria, such as Staphylococcus aureus, by preventing the production of extracellular polysaccharides. This compound also binds to κ-opioid receptors in the brain and has been shown to block pain transmission. N-tritylimidazole can be synthesized using a cross-coupling reaction with phenylboronic acid and chloroiodomethane, which requires hydrochloric acid as a catalyst.

• Brand: Biosynth

Chemical properties

• Molecular weight: 310.39 g/mol
• Formula: C₂₂H₁₈N₂
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C22H18N2/c1-4-10-19(11-5-1)22(24-17-16-23-18-24,20-12-6-2-7-13-20)21-14-8-3-9-15-21/h1-18H
• InChI key: InChIKey=NPZDCTUDQYGYQD-UHFFFAOYSA-N
• SMILES: c1ccc(C(c2ccccc2)(c2ccccc2)n2ccnc2)cc1