1-(3-Trifluoromethylphenyl)piperazine hydrochloride

CAS: 16015-69-3

Ref. 3D-FT38536

Product Information

• Name: 1-(3-Trifluoromethylphenyl)piperazine hydrochloride
• Brand: Biosynth
• Description: 1-(3-Trifluoromethylphenyl)piperazine hydrochloride (TFMPP) is a derivative of the piperazine class of drugs. It is structurally similar to other drugs in this class, such as bromopropane, which acts as an agonist of the 5-HT1 receptor. TFMPP has been shown to be an agonist at 5-HT1 receptors and dopamine receptors. It has also been shown to inhibit serotonin uptake and release, and inhibits choline acetyltransferase activity in brain tissue. TFMPP is not active on the 5-HT2 receptor, but does have some affinity for the 5-HT2A receptor. TFMPP has high affinity for the serotonergic system, with selective binding to serotonin transporter proteins in vitro. TFMPP may also have some effect on cholinergic systems through its inhibition of acetylcholinesterase activity.

Chemical properties

• Molecular weight: 266.69 g/mol
• Formula: C₁₁H₁₄ClF₃N₂
• Purity: Min. 95%
• Color/Form: White Powder