Product Information
- Acetamide, N-(4-amino-2-methylphenyl)-
4-Amino-2-methylphenylacetic acid (AMPA) is a chemical compound that has been used in the treatment of skin disorders. AMPA is not active when applied to the skin, but it can be converted to 4-amino-2-methylphenylacetamide (AMPAA), which is an effective treatment for psoriasis. This conversion can be achieved with keratinocyte cells, which are found in the outer layer of skin. The optimal conditions for this conversion include coculturing keratinocytes and thp-1 cells over a period of 48 hours. This process was demonstrated using a human keratinocyte cell line and thp-1 cells. The sensitivity of these cells to AMPA was tested by exposing them to increasing concentrations of AMPA until they were killed. The results showed that AMPA had no effect on keratinocyte cells, but at higher concentrations it had an adverse effect on thp-1 cells. It was also
Chemical properties
Technical inquiry about: 3D-GCA89159 N-(4-Amino-2-methylphenyl)acetamide
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