6-Chloro-4-(2-chlorophenyl)-2-quinazolinecarboxylic acid

CAS: 54643-79-7

Ref. 3D-IC76691

Product Information

• Name: 6-Chloro-4-(2-chlorophenyl)-2-quinazolinecarboxylic acid
• Synonyms: Lorazepam related compound D
• Brand: Biosynth
• Description: 6-Chloro-4-(2-chlorophenyl)-2-quinazolinecarboxylic acid (CA) is an impurity found in the drug lorazepam. It is a chemical intermediate that is not active as a pharmaceutical agent, but has been studied for use in treating epilepsy and other neurological disorders. CA is an excipient used to manufacture other drugs such as salicylic acid and the surfactant sodium lauryl sulfate. It has been shown to have acidic properties and can be used as a surfactant, which is helpful in chromatographic methods to separate molecules by size. CA also binds to chloride ions, which are necessary for the proper functioning of many cellular processes. CA's molecular weight is 322 daltons and it exhibits no pharmacological activity.

Chemical properties

• Molecular weight: 319.14 g/mol
• Formula: C₁₅H₈Cl₂N₂O₂
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C15H8Cl2N2O2/c16-8-5-6-12-10(7-8)13(19-14(18-12)15(20)21)9-3-1-2-4-11(9)17/h1-7H,(H,20,21)
• InChI key: InChIKey=WPSNLOADPUPVMP-UHFFFAOYSA-N
• SMILES: O=C(O)c1nc(-c2ccccc2Cl)c2cc(Cl)ccc2n1