Pitavastatin 3S,5R isomer calcium
CAS: 254452-88-5
Ref. 3D-IP145451
| 1mg | 192.00 € | ||
| 2mg | 303.00 € | ||
| 5mg | 497.00 € | ||
| 10mg | 711.00 € | ||
| 25mg | 924.00 € |
Product Information
- (3S,5R)-3,5-Dihydroxy-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-6-heptenoic acid
- 6-Heptenoic acid, 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-, calcium salt (2:1), (3S,5R,6E)-
- ent-NK-104
Pitavastatin 3S,5R isomer Calcium Salt is a potent inhibitor of cholesterol biosynthesis. It is marketed as the hemihydrate form under the trade name Pravacol and is used in the treatment of type 2 diabetes. Pitavastatin 3S,5R isomer Calcium Salt inhibits cholesterol biosynthesis by blocking HMG-CoA reductase, which converts 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) to mevalonate (MVA). The active metabolite, pitavastatin, binds to the regulatory region of HMG-CoA reductase and prevents it from converting MVA to HMG-CoA. This reduces the pool of HMG-CoA available for conversion to cholesterol. The inhibition of this enzyme slows down the production of cholesterol and decreases blood levels. It has been approved for use in adults with type 2 diabetes and for lowering high
Chemical properties
Technical inquiry about: 3D-IP145451 Pitavastatin 3S,5R isomer calcium
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