Product Information
- 4-phenyl-1,2,5-oxadiazol-3-amine
- 1,2,5-oxadiazol-3-amine, 4-phenyl-
4-Phenyl-1,2,5-oxadiazol-3-amine is an analog of histamine that acts as a competitive antagonist at the H2 receptor. This compound has been shown to elicit histamine release in guinea pig tissues and to act as a competitive antagonist at the H2 receptor. It also blocks histamine binding to other receptors and has been shown to have antihistaminic properties. 4-Phenyl-1,2,5-oxadiazol-3-amine binds in a similar fashion as cimetidine and ranitidine with high affinity for the H2 receptor and lower affinity for the H1 receptor. This drug has also been shown to inhibit guinea pig ileum contractions and rat vas deferens contractions induced by histamine. The molecular weight of this compound is 169.4 g/mol and its chemical formula is C9H7N3O3. The structural formula is:
Chemical properties
Technical inquiry about: 3D-KAA34914 4-Phenyl-1,2,5-oxadiazol-3-amine
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