
4-Amino-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
CAS:
Ref. 3D-NA144556
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Product Information
Name:4-Amino-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
Synonyms:
- 2'-C-Methyl toyocamycin
Brand:Biosynth
Description:4-Amino-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (PMPC) is a novel antiviral agent. It is highly active against HIV and has shown to be effective against herpes simplex virus type 1 (HSV1) and HSV type 2 (HSV2). PMPC inhibits the synthesis of viral DNA by phosphorylating a monophosphate residue on the ribonucleoside triphosphate substrate. This prevents the enzyme from adding another phosphate group to the nucleotide sequence, which prevents further DNA synthesis. PMPC also has anticancer properties due to its ability to inhibit cell proliferation by preventing the formation of deoxyribonucleosides and diphosphates.
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Chemical properties
Molecular weight:305.29 g/mol
Formula:C13H15N5O4
Purity:Min. 95%
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