7-(Aminomethyl)-7-deazaguanosine
CAS: 66048-70-2
Ref. 3D-NA159479
| 1mg | To inquire | ||
| 5mg | To inquire | ||
| 10mg | To inquire |
Product Information
- 2- Amino- 5- (aminomethyl) - 1
- 7- dihydro- 7- b- D- ribofuranosyl-4H- pyrrolo[2
- 3- d] pyrimidin- 4- one
7-Aminomethyl-7-deazaguanosine is a nucleoside that is classified as a purine. It can be synthesized from 7-amino-7-deazaguanosine and sodium periodate. The chemical reactions involved in the synthesis are oxidation of the amine group on the 7-amino group to form an iminium ion and subsequent nucleophilic attack by the hydroxyl group on the N9 position of the purine ring to form an amino alcohol. This nucleoside has been shown to bind to ribosomes and inhibit protein synthesis, which suggests that it may have potential for use as an antibiotic or anticancer agent. 7-Aminomethyl-7-deazaguanosine has also been shown to cause epigenetic changes such as DNA methylation, histone modification, and alterations in chromatin structure.
Chemical properties
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