(2'R)-N-Benzoyl-2'-deoxy-2'-fluoro-2'-methylcytidine 3',5'-d

CAS: 817204-32-3

Ref. 3D-NB98842

Product Information

• Name: (2'R)-N-Benzoyl-2'-deoxy-2'-fluoro-2'-methylcytidine 3',5'-d
• Synonyms: ((2R,3R,4R,5R)-5-(benzamido-2-oxopyrimidin-1(2H)-yl)-2-(benzoyloxymethyl)-4-fluoro-4-methyltetrahydrofuran-3-yl, (2'R)-N-Benzoyl-2'-deoxy-2'-fluoro-2'-methylcytidine 3',5'-dibenzoate, (2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate, (2R,3R,4R,5R)-5-4-benzamide-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate, 2'-Deoxy-2'-Fluoro-2'-Methyl-N-(Phenylcarbonyl) Cytidine, 3',5'-O-4-Tribenzoyl-2'-deoxy-2'-fluoro-2'-C-methylcytidine, Cytidine, N-benzoyl-2′-deoxy-2′-fluoro-2′-methyl-, 3′,5′-dibenzoate, (2′R)-, N-benzoyl-3,5-di-O-benzoyl-2-deoxy-2-fluoro-2-methylcytidine, PSI-6130 derivative, Sofosbuvir N-3, [(2R,3R,4R,5R)-5-(4-benzamido-2-oxo-1,2-dihydropyrimidin-1-yl)-3-(benzoyloxy)-4-fluoro-4-methyloxolan-2-yl]methyl benzoate

Description

(2'R)-N-Benzoyl-2'-deoxy-2'-fluoro-2'-methylcytidine 3',5'-diphosphate (2'R)-N-benzoyl-2'-deoxy-2'-fluoro-2'-methylcytidine 3',5'-diphosphate) is a modified nucleoside that is an antiviral, anticancer, and activator of DNA synthesis. It has been shown to be the first synthetic nucleotide analogue to have significant activity against HIV in vitro. The synthesis of this compound starts with the diphosphate or monophosphate form of cytidine. The phosphate group is removed and replaced with a 2'R benzoyl group. This process is followed by fluorination and methylation steps. Finally, the 5' hydroxyl group is cleaved to give 2'R -N benzoyl 2'-deoxy-2'-fluoro-2'-

• Brand: Biosynth

Chemical properties

• Molecular weight: 571.55 g/mol
• Formula: C₃₁H₂₆FN₃O₇
• Purity: Min. 95%