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2'-Deoxy-5-fluorouridine
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2'-Deoxy-5-fluorouridine

CAS: 50-91-9

Ref. 3D-ND02921

2g
109.00 €
5g
170.00 €
10g
241.00 €
25g
464.00 €
50g
733.00 €
Estimated delivery in United States, on Monday 22 Apr 2024

Product Information

Name:
2'-Deoxy-5-fluorouridine
Synonyms:
  • 5-Fluoro-2'-deoxy-D-uridineFloxuridine2'-Deoxy-5-fluoro-D-uridine5-Fluoro-2'-deoxyuridine
  • (+)-5-Fluorodeoxyuridine
  • 1-(2-Deoxy-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-5-fluorouracil
  • 1-(2-Deoxy-β-D-ribofuranosyl)-5-fluorouracil
  • 1-(2-deoxy-D-threo-pentofuranosyl)-5-fluoropyrimidine-2,4(1H,3H)-dione
  • 1-(2-deoxypentofuranosyl)-5-fluoropyrimidine-2,4(1H,3H)-dione
  • 2-Deoxy-5-fluorouridine
  • 5-Fluoro-2'-deoxy-β-uridine
  • 5-Fluoro-2?Deoxy Uridine
  • 5-Fluorouracil 2'-deoxyriboside
  • See more synonyms
  • 5-Fluorouracil deoxyriboside
  • 5-Fudr
  • Deoxyfluorouridine
  • FdUrd
  • Floxiridina
  • Floxuridin
  • Floxuridine
  • Fudr
  • Nsc 26740
  • Nsc 27640
  • Uridine, 2'-deoxy-5-fluoro-
Description:

2'-Deoxy-5-fluorouridine is a nucleoside analog that inhibits the enzyme ribonucleotide reductase, which is involved in the synthesis of DNA. It has been shown to inhibit the growth of cancer cells and induce apoptosis in vivo. 2'-Deoxy-5-fluorouridine has also been shown to inhibit tumor growth in animal models by inhibiting the production of reactive oxygen species and upregulating tumor suppressor genes, such as p53. This drug also has inhibitory effects on enzymes that are involved in cell proliferation, such as protein kinase C and tyrosine kinases. 2'-Deoxy-5-fluorouridine is metabolized by water vapor, so it must be administered with a humidifier or nebulizer. 2'-Deoxy-5-fluorouridine may cause side effects such as nausea, vomiting, and diarrhea.

Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
246.2 g/mol
Formula:
C9H11FN2O5
Purity:
Min. 98 Area-%
Color/Form:
White Off-White Powder
MDL:
Melting point:
Boiling point:
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Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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