2'-Deoxy-N2-isobutyrylguanosine

CAS: 68892-42-2

Ref. 3D-ND02989

Product Information

• Name: 2'-Deoxy-N2-isobutyrylguanosine
• Synonyms: N2-Isobutyryl-2'-deoxyguanosine2'-Deoxy-N2-isobutyryl-D-guanosine, N2-Isobutyryl-2-deoxyguanosine (dG-iBu), Ibu-Deoxyguanosine, dG-Ibu, N2-Isobutyryl-2'-deoxyguanosine, Guanosine, 2'-deoxy-N-(2-methyl-1-oxopropyl)-, N-Ib-Dg, N2-Isobutyryldeoxyguanosine, N2-Isobutyl-2'-Deoxyguanosine, N2-Isobutyroyl-2'-Deoxyguanosine, N2-(Ibu)-2'-Deoxyguanosine, N2-(2-Methylpropanoyl)-2'Deoxy-Guanosine, 2'-deoxy-N-(2-methylpropanoyl)guanosine, 2'-deoxy-N-(2-methylpropyl)guanosine

Description

2'-Deoxy-N2-isobutyrylguanosine (2'-DIBG) is an inhibitor of bacterial translocation that has been shown to inhibit the growth of several bacterial species. This drug binds to fatty acids, which are important for maintaining the integrity of the cell membrane and preventing bacterial translocation. 2'-DIBG also inhibits the production of reactive oxygen species by bacteria, which contributes to its antimicrobial activity. Inflammation can be reduced by inhibiting prostaglandin synthesis with 2'-DIBG. The inhibition of prostaglandin synthesis may be due to its ability to form acid conjugates with fatty acids and dicarboxylic acids, which are precursors for prostaglandins. 2'-DIBG also inhibits the synthesis of adenosine triphosphate (ATP) in bacteria, leading to a decrease in bacterial growth rate.

• Brand: Biosynth

Chemical properties

• Molecular weight: 337.34 g/mol
• Formula: C₁₄H₁₉N₅O₅
• Purity: Min. 95%
• Color/Form: White Powder