5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine
CAS: 163759-50-0
Ref. 3D-ND36302
| 1g | 493.00 € | ||
| 2g | 912.00 € | ||
| 100mg | 172.00 € | ||
| 250mg | 246.00 € | ||
| 500mg | 351.00 € |
Product Information
- 5'-O-DMT-2'-O-MOE-5-methyluridine
- 5'-O-Dmtr- 2'-O-(2-Methoxyethyl)-5-Methyl-Uridine
- 5'-O-(Bis(4-Methoxyphenyl)Phenylmethyl)-2'-O-(2-Methoxyethyl)-5-Methyluridine
5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine is a novel, synthetic nucleoside with antiviral and antitumor activity. It is an analogue of 5'-O-DMT-2'-O-(2-methoxyethyl)uridine, which has been shown to be active against herpes simplex virus type 1 (HSV1) in vitro. The phosphoramidites of 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine are modified at the 2' position with a methyl group and at the 5' position with a methoxyethyl group. These modifications make it more resistant to degradation by intracellular enzymes. The anticancer activity of 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine was demonstrated in preclinical studies using human tumor cell lines.
Chemical properties
Technical inquiry about: 3D-ND36302 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine
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