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Disialyl-TF
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Disialyl-TF

CAS: 71764-07-3

Ref. 3D-OD58489

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Estimated delivery in United States, on Monday 22 Apr 2024

Product Information

Name:
Disialyl-TF
Synonyms:
  • NeuNAca2-3Galb1-3(NeuNAc2-6)GalNAcDisialyl Galacto-N-biose
  • (2S,4S,5R,6R)-5-acetamido-2-[(2R,3R,4S,5S,6R)-2-[(2R,3R,4S,5R)-2-acetamido-6-[(2R,4S,5R,6R)-5-acetamido-2-carboxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxan-2-yl]oxy-4,5-dihydroxy-1-oxo-hexan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid
  • <span class="text-smallcaps">D</smallcap>-Galactose, O-(N-acetyl-α-neuraminosyl)-(2→6)-O-[O-(N-acetyl-α-neuraminosyl)-(2→3)-β-<smallcap>D</span>-galactopyranosyl-(1→3)]-2-(acetylamino)-2-deoxy-
  • Disialosyl galactosyl globoside
  • O-(N-Acetyl-α-neuraminosyl)-(2→6)-O-[O-(N-acetyl-α-neuraminosyl)-(2→3)-β-<span class="text-smallcaps">D</smallcap>-galactopyranosyl-(1→3)]-2-(acetylamino)-2-deoxy-<smallcap>D</span>-galactose
Description:

Disialyl-TF is a monoclonal antibody that binds to the CD33 antigen on the surface of all types of cancer cells, including breast cancer cells. Disialyl-TF has been shown to reduce the growth and spread of prostate cancer cells in mice, reducing tumor size and weight. Disialyl-TF is also active against infectious diseases such as HIV, which may be due to its ability to inhibit the expression of glycan receptors. The mechanism by which it works is not yet known. Disialyl-TF has been shown to bind with high affinity to erythrocytes bearing A or B blood group antigens, making it an excellent diagnostic tool for detecting these antigens in patients with acute myeloid leukemia or other cancers.

Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
965.86 g/mol
Formula:
C36H59N3O27
Purity:
Min. 95%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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