2'-Deoxy-5'-O-DMT-N2-(4-isopropylphenoxyacetyl)guanosine 3'-Me phosphoramidite
Ref. 3D-PD09146
| 1g | 526.00 € | ||
| 2g | 979.00 € | ||
| 250mg | 340.00 € | ||
| 500mg | 343.00 € |
Product Information
- 5'-(4,4'-Dimethoxytrityl)-N-(4-isopropylphenoxyacetyl)-2'-deoxyguanosine
- 3'- [methyl-(N,N-diisopropyl)]-phosphoramiditeiPr-Pac-dG- Me Phosphoramidite2'-Deoxy-5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-D-guanosine 3'-Me phosphonamidite5'-O-DMT-N2-(4-is
2'-Deoxy-5'-O-DMT-N2-(4-isopropylphenoxyacetyl)guanosine 3'-Me phosphoramidite is a modified nucleoside monophosphate with antiviral and anticancer activity. It is synthesized by the reaction of 2'-deoxyguanosine 5'-O-DMT (dG) with 4-isopropylphenoxyacetic acid in the presence of triethylamine and tetrazole. The product is purified by crystallization.
This compound has been shown to inhibit replication of human immunodeficiency virus type 1 (HIV-1) in human lymphocytes, which may be due to its ability to inhibit the synthesis of DNA, RNA, or both.
Chemical properties
Technical inquiry about: 3D-PD09146 2'-Deoxy-5'-O-DMT-N2-(4-isopropylphenoxyacetyl)guanosine 3'-Me phosphoramidite
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