CoV-2 S1 (319-541), Sf9

Ref. 3D-SARS-049

Product Information

• Name: CoV-2 S1 (319-541), Sf9
• Synonyms: Coronavirus 2019-nCoV Spike Glycoprotein-S1 Receptor Binding Domain Recombinant,SF9 Severe acute respiratory syndrome coronavirus 2 COVID-19 COVID-19 virus COVID19 HCoV-19 Human coronavirus 2019 SARS-2 SARS-CoV2 SARS2 SARS-CoV-2 SP RBD 2019-nCo
• Brand: Biosynth
• Description: A human infecting coronavirus (viral pneumonia) called 2019 novel coronavirus, 2019-nCoV was found in the fish market at the city of Wuhan, Hubei province of China on December 2019.The 2019-nCoV shares an 87% identity to the 2 bat-derived severe acute respiratory syndrome 2018 SARS-CoV-2 located in Zhoushan of eastern China. 2019-nCoV has an analogous receptor-BD-structure to that of 2018 SARS-CoV, even though there is a.a. diversity so thus the 2019-nCoV might bind to ACE2 receptor protein (angiotensin-converting enzyme 2) in humans.While bats are probably the host of 2019-nCoV, researchers suspect that animal from the ocean sold at the seafood market was an intermediate host. RSCU analysis proposes that the 2019-nCoV is a recombinant within the viral spike glycoprotein between the bat coronavirus and an unknown coronavirus.Recombinant Coronavirus 2019-nCoV Spike Glycoprotein-S1 Receptor Binding Domain is a single, glycosylated polypeptide chain containing a total of 232 amino acids (319-541) and having a calculated M.W. of 26.2 kDa. CoV-2 S1 (319-541) is fused to a 6 amino acid His-tag at C-terminus,and is purified by proprietary chromatographic techniques. The source of Sf9 is from Baculovirus cells and the formulation of the CoV-2 S1 (319-541) solution (0.25mg/ml) contains Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol. Its biological activity has been measured by its binding ability in a functional ELISA with Human ACE-2.One-Letter Formula: ADPRVQPTES IVRFPNITNL CPFGEVFNAT RFASVYAWNR KRISNCVADY SVLYNSASFS TFKCYGVSPT KLNDLCFTNV YADSFVIRGD EVRQIAPGQT GKIADYNYKL PDDFTGCVIA WNSNNLDSKV GGNYNYLYRL FRKSNLKPFE RDISTEIYQA GSTPCNGVEG FNCYFPLQSY GFQPTNGVGY QPYRVVVLSF ELLHAPATVC GPKKSTNL

Chemical properties

• Purity: Min. 95%