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1-[3-(Bromomethyl)phenyl]-2,2,2-trifluoroethan-1-one

CAS:

Ref. 3D-VPA10405

50mg
790.00€
500mg
2,303.00€
1-[3-(Bromomethyl)phenyl]-2,2,2-trifluoroethan-1-one
Biosynth

Product Information

Name:1-[3-(Bromomethyl)phenyl]-2,2,2-trifluoroethan-1-one
Brand:Biosynth
Description:1-[3-(Bromomethyl)phenyl]-2,2,2-trifluoroethan-1-one is a potent and selective inhibitor of acetylcholinesterase, with nanomolar range of inhibition. The crystal structure of 1-[3-(Bromomethyl)phenyl]-2,2,2-trifluoroethan-1-one has been determined. It is a white crystalline solid that is soluble in water. This compound has validated activity against acetylcholinesterase and molecular modeling studies have been conducted to elucidate the mode of binding to the active site. The postulated mechanism for inhibition includes complexation with an enzyme moiety (a serine residue) and the formation of a covalent bond with an electrophilic center on the enzyme that can be attacked by a nucleophile on the inhibitor molecule.
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Chemical properties

Molecular weight:267.04 g/mol
Formula:C9H6BrF3O
Purity:Min. 95%

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