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8-O-Acetyl shanzhiside methyl ester

CAS: 57420-46-9

Ref. BP-BP0110

274.00 €
613.00 €
Estimated delivery in United States, on Wednesday 4 Mar 2020

Product Information

8-O-Acetyl shanzhiside methyl ester
  • Barlerin; Umbroside
Long term storage:
Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.

8- O -acetyl Shanzhiside Methylester can increases angiogenesis and improve functional recovery after stroke.[2]
8-O-acetyl shanzhiside methylester (ND01), an iridoid glucoside compound, was isolated from the leaves of Lamiophlomis rotata (Benth.) Kudo, ND01 has potential against cerebral ischemic injury, and its protective effect on oxygen–glucose deprivation-induced injury might be due to the suppression of intracellular Ca 2+ elevation and caspase-3 activity, and improvement of mitochondrial energy metabolism.[1]
8-O-acetyl shanzhiside methylester has protective effects on experimental myocardial ischemia injury, the effects might be due to block of myocardial inflammatory cascades through an HMGB1-dependent NF-κB signaling pathway.[3]
8-O-acetyl shanzhiside methylester protects diabetic brain against I/R injury by alleviating diabetic cerebral I/R injury and attenuating blood–brain barrier (BBB) breakdown, and its protective effects may involve HMGB-1 and NF-κB signalling pathway.[4]
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The product could be supplied from milligrams to grams, up to kilograms
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.
analysis-method: HPLC-DAD or/and HPLC-ELSD
botanical-source: Barleria prionitis
identification-method: Mass, NMR
type-of-compound: Iridoids

Chemical properties

Molecular weight:

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