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Alpha-Hederin

Alpha-Hederin

CAS 27013-91-8

Ref. BP-BP0154

20mg
100mg
1000mg
193.00 €
261.00 €
688.00 €
Estimated delivery time: ~13 days

Product Information

Name:
Alpha-Hederin
Long term storage:
Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Notes:

Alpha-Hederin can increase isoprenaline-induced relaxation indirectly, probably by inhibiting heterologous desensitization induced by high concentrations of muscarinic ligands like .[6]
Alpha-hederin affects the binding behavior, dynamics, and regulation of beta 2-adrenergic receptors.[5]
Alpha-hederin as a pro-drug, has cytotoxic and apoptotic/necrotic effects in a dose- and time-dependent manner on on four human cancer cell lines [A549 (lung carcinoma), HEp-2 (larynx epidermoid carcinoma), HT-29 (colon adenocarcinoma) and MIA PaCa-2 (pancreas carcinoma)] .[1]
Alpha-hederin at sub-IC(50) cytotoxic concentrations enhances 5-fluorouracil (5-FU) cytotoxicity about 3.3-fold, suggests that it is possible to optimize colorectal cancer cell sensitivity to 5-FU with alpha-hederin.[7]
Alpha-hederin has anticancer effect on breast cancer cells.[8]
Alpha-hederin has antileishmanial activity ,exhibits a strong antiproliferative activity on all stages of development of the parasite by altering membrane integrity and potential in Leishmania .[4]
Alpha-hederin is a saponin isolated from ivy, has anti-oxidant activity and acute anti-inflammatory activity in carrageenan-induced rat paw edema.[2]
Alpha-hederin, chlorophyllin and ascorbic acid have protective effects towards the induction of micronuclei by doxorubicin in cultured human lymphocytes.[3]
Inquire for bulk scale.
The product could be supplied from milligrams to grams, up to kilograms
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.
analysis-method: HPLC-DAD or/and HPLC-ELSD
botanical-source: Hedera helix; Chinese ivy; Hedera nepalensis K,Koch var.sinensis (Tobl.) Rehd
identification-method: Mass, NMR
type-of-compound: Triterpenoids


Chemical properties

Molecular weight:
750.967
Formula:
C41H66O12
Purity:
98%
Color/Form:
Powder

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