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Asiatic acid

CAS: 464-92-6

Ref. BP-BP0203

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Estimated delivery in United States, on Wednesday 17 Jun 2020

Product Information

Asiatic acid
  • Dammarolic acid
Long term storage:
Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.

Asiatic acid (AA) has anti-inflammatory and antioxidant effects, it inhibits LPS-induced ALI in mice by inhibiting inflammatory cytokine production, which is mediated via blocking of the TLR4/NF-kB signaling pathway.[5]
Asiatic acid ameliorates dextran sulfate sodium-induced murine experimental colitis via suppressing mitochondria-mediated NLRP3 inflammasome activation, its potential usage in the treatment of inflammatory bowel disease.[3]
Asiatic acid can inhibit cell proliferation through regulating the expression of focal adhesion kinase in multiple myeloma cells.[6]
Asiatic acid has been reported to induce apoptosis of various human cancer cells, it may exert anti-tumorigenesis through inhibitory actions in NO and COX-2 signals.[2]
Asiatic acid is a pentacyclic triterpene contained in medicinal plants, can be used as an agent for increasing sensitivity of colon cancer cells to treatment with CPT-11 or as an agent for reducing adverse effects of CPT-11.[1]
Asiatic acid shows antidiabetic and antihyperlipidemic activity in diabetic rats.[4]
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The product could be supplied from milligrams to grams, up to kilograms
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.
analysis-method: HPLC-DAD or/and HPLC-ELSD
botanical-source: Dipterocarpus pilosus, Dryobalanops aromatica and others
identification-method: Mass, NMR
type-of-compound: Triterpenoids

Chemical properties

Molecular weight:

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