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Beta-Eudesmol

Beta-Eudesmol

CAS 473-15-4

Ref. BP-BP0263

20mg
309.00 €
Estimated delivery time: ~13 days

Product Information

Name:
Beta-Eudesmol
Synonyms:
  • 4(15)-Selinen-11-ol
Long term storage:
Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Notes:

Beta-eudesmol has potential anti-angiogenic and anti-tumour activities, it inhibits angiogenesis by suppressing CREB activation in growth factor signalling pathway, is an inhibitor of tumour growth.[3]
Beta-eudesmol induces apoptosis is accompanied by cleavage of caspase-3, caspase-9, and poly (ADP-ribose) polymerase; downregulation of Bcl-2 expression; release of cytochrome c from mitochondria; and decrease in mitochondrial membrane potential (MMP), suggests it induces apoptosis in HL60 cells via the mitochondrial apoptotic pathway, which is controlled through JNK signaling. [4]
Beta-eudesmol induces neurite outgrowth in rat pheochromocytoma cells accompanied by an activation of mitogen-activated protein kinase, it may be a promising lead compound for potentiating neuronal function, and the drug may be useful in helping to clarify the mechanisms underlying neuronal differentiation.[2]
Beta-eudesmol, a sesquiterpenoid alcohol isolated from Atractylodes lancea rhizome, can inhibit angiogenesis, at least in part, through the blockade of the ERK signaling pathway, suggests that it may aid the development of drugs to treat angiogenic diseases.[1]
Inquire for bulk scale.
The product could be supplied from milligrams to grams, up to kilograms
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.
analysis-method: HPLC-DAD or/and HPLC-ELSD
botanical-source: eucalyptus oils. A widely distrib. essential oils, freq. not differentiated from α-Eudesmol
identification-method: Mass, NMR
type-of-compound: Sesquiterpenoids


Chemical properties

Molecular weight:
222.372
Formula:
C15H26O
Purity:
98%
Color/Form:
White cryst.

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