AS2863619 free base
CAS: 2241300-50-3
Ref. TM-T10382
25mg | 916.00 € | ||
50mg | 1,273.00 € | ||
100mg | 1,741.00 € | ||
1ml*10 (DMSO) | 357.00 € |
Product Information
AS2863619 free base enables the conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells. It is a potent, orally active CDK8 and CDK19 inhibitor (IC50s: 0.61 nM and 4.28 nM). STAT5 activation enhanced by AS2863619 free base inhibition of CDK8/19, which consequently activates the Foxp3 gene.
Chemical properties
Technical inquiry about: TM-T10382 AS2863619 free base
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