CHMFL-PI3KD-317
CAS: 2244992-76-3
Ref. TM-T10804
| 1mg | 108.00 € | ||
| 5mg | 260.00 € | ||
| 10mg | 416.00 € | ||
| 25mg | 691.00 € | ||
| 50mg | 922.00 € | ||
| 100mg | 1,299.00 € | ||
| 500mg | 2,619.00 € | ||
| 1ml*10 (DMSO) | 276.00 € |
Product Information
CHMFL-PI3KD-317 is a highly potent, selective and orally active PI3Kδ inhibitor, with an IC50 of 6 nM, and exhibits over 10-1500 fold selectivity over other class I, II and III PIKK family isoforms, such as PI3Kα (IC50, 62.6 nM), PI3Kβ (IC50, 284 nM), PI3Kγ (IC50, 202.7 nM), PIK3C2A (IC50, >10000 nM), PIK3C2B (IC50, 882.3 nM), VPS34 (IC50, 1801.7 nM), PI4KIIIA (IC50, 574.1 nM) and PI4KIIIB (IC50, 300.2 nM). CHMFL-PI3KD-317 inhibits PI3Kδ-mediated Akt T308 phosphorylation in Raji cells, with an EC50 of 4.3 nM. CHMFL-PI3KD-317 has antiproliferative effects on cancer cells.
Chemical properties
Technical inquiry about: TM-T10804 CHMFL-PI3KD-317
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