GW274150
CAS: 210354-22-6
Ref. TM-T11518L
1mg | 114.00 € | ||
5mg | 258.00 € | ||
10mg | 379.00 € | ||
25mg | 611.00 € | ||
50mg | 835.00 € | ||
100mg | 1,252.00 € | ||
500mg | To inquire |
Product Information
- GW-274150
- (S)-4-((2-Acetimidamidoethyl)thio)-2-aminobutanoic acid
- 2(S)-Amino-7-(1-iminoethylamino)-5-thiaheptanoic acid
- 274150
- <span class="text-smallcaps">L</span>-Homocysteine, S-[2-[(1-iminoethyl)amino]ethyl]-
- Gw-274150
- S-[2-[(1-Iminoethyl)amino]ethyl]-<span class="text-smallcaps">L</span>-homocysteine
GW274150 is an orally active, selective and potent dual inhibitor of NADPH-dependent human nitric oxide synthase (iNOS) (Kd=40 nM) and rat inducible nitric oxide synthase (iNOS).GW274150 has a low activity against endothelial nitric oxide synthase (eNOS) and neuronal nitric oxide synthase (nNOS) in humans and rats. GW274150 showed protective effects in an inflammatory model of acute lung injury.
Chemical properties
Technical inquiry about: TM-T11518L GW274150
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