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PROTAC Mcl1 degrader-1
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PROTAC Mcl1 degrader-1

CAS: 2163793-38-0

Ref. TM-T11975

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Estimated delivery in United States, on Monday 6 May 2024

Product Information

Name:
PROTAC Mcl1 degrader-1
Synonyms:
  • PROTAC Mcl-1 degrader-1
  • PROTAC Mcl1 degrader1
Description:

PROTAC Mcl1 degrader-1 induces the ubiquitination and proteasomal degradation of Mcl-1 by introducing the E3 ligase cereblon (CRBN)-binding ligand pomalidomide to Mcl-1 inhibitor S1-6 with μM-range affinity. PROTAC Mcl1 degrader-1, a proteolysis targeting chimera (PROTAC), is a potently and selectively Mcl-1 inhibitor with an IC50 of 0.78 μM.

Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
909.84
Formula:
C45H45BrN6O8S
Purity:
98%
Color/Form:
Solid
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

Technical inquiry about: TM-T11975 PROTAC Mcl1 degrader-1

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