PROTAC Mcl1 degrader-1
CAS: 2163793-38-0
Ref. TM-T11975
1mg | To inquire | |
5mg | To inquire | |
10mg | To inquire | |
50mg | To inquire | |
100mg | To inquire |
Product Information
- PROTAC Mcl-1 degrader-1
- PROTAC Mcl1 degrader1
PROTAC Mcl1 degrader-1 induces the ubiquitination and proteasomal degradation of Mcl-1 by introducing the E3 ligase cereblon (CRBN)-binding ligand pomalidomide to Mcl-1 inhibitor S1-6 with μM-range affinity. PROTAC Mcl1 degrader-1, a proteolysis targeting chimera (PROTAC), is a potently and selectively Mcl-1 inhibitor with an IC50 of 0.78 μM.
Chemical properties
Technical inquiry about: TM-T11975 PROTAC Mcl1 degrader-1
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