Product Information
ML218 inhibits the burst activity in the subthalamic nucleus (STN) neurons. ML218 is an effective, selective, and orally active inhibitor of T-type Ca2+ channel (Cav3.1, Cav3.2, Cav3.3) (IC50s: 310 nM and 270 nM for Cav3.2 and Cav3.3, respectively). ML218 can penetrate the blood-brain barrier. ML218 has no significant inhibition of L- or N-type calcium channels, KATP, or hERG potassium channels.
Chemical properties
Technical inquiry about: TM-T12076L ML218
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.