Diacerein

CAS: 13739-02-1

Ref. TM-T1273

Product Information

• Name: Diacerein
• Synonyms: Diacerhein, Fisiodar, Diacetylrhein, 1,8-Diacetoxy-3-carboxyanthraquinone, 2-Anthracenecarboxylic acid, 4,5-bis(acetyloxy)-9,10-dihydro-9,10-dioxo-, 2-Anthroic acid, 9,10-dihydro-4,5-dihydroxy-9,10-dioxo-, diacetate, 4,5-Bis(Acetyloxy)-9,10-Dioxo-9,10-Dihydroanthracene-2-Carboxylic Acid, 4,5-Bis(acetyloxy)-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic acid, 4,5-Bis(acetyloxy)-9,10-dioxo-2-anthracenecarboxylic acid, 4,5-Diacetoxy-9,10-dioxoanthracene-2-carboxylic acid, 4,5-Diacetoxyanthraquinone-2-carboxylic acid, 4,5-Diacetylrhein, Ac 201, Artrodar, Diacerhein, Diacetylrhein, Fisiodar, Inflabion, Osteocerein, Rhein, diacetate, Sf 277
• CAS: 13739-02-1

Description

Diacerein (Fisiodar) is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is restricted due to the side effects including sevre diarrhea [L780]. Diacerein is under investigation for the treatment of Insulin Resistance, Diabetes Mellitus (Type 2), and Diabetes-Related Complications.

• Brand: Targetmol

Chemical properties

• Molecular weight: 368.29
• Formula: C₁₉H₁₂O₈
• Purity: 98.14%
• Color/Form: Solid
• InChI: InChI=1S/C19H12O8/c1-8(20)26-13-5-3-4-11-15(13)18(23)16-12(17(11)22)6-10(19(24)25)7-14(16)27-9(2)21/h3-7H,1-2H3,(H,24,25)
• InChI key: InChIKey=TYNLGDBUJLVSMA-UHFFFAOYSA-N
• SMILES: CC(=O)Oc1cccc2c1C(=O)c1c(OC(C)=O)cc(C(=O)O)cc1C2=O