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1-Naphthohydroxamic acid

CAS: 6953-61-3

Ref. TM-T13996

5mg
55.00 €
10mg
94.00 €
25mg
180.00 €
50mg
347.00 €
100mg
517.00 €
500mg
1,133.00 €
1ml*10 (DMSO)
62.00 €
Estimated delivery in United States, on Wednesday 8 May 2024

Product Information

Name:
1-Naphthohydroxamic acid
Synonyms:
  • 1-Naphthalenecarboxamide, N-hydroxy-
  • N-Hydroxy-1-naphthalenecarboxamide
  • N-hydroxynaphthalene-1-carboxamide
  • NSC 57457
  • α-Naphthohydroxamic acid
Description:

1-Naphthohydroxamic acid (Compound 2) is a potent and selective HDAC8 inhibitor with an IC50 of 14 μM, and it is more selectively for HDAC8 than class I HDAC1 and class II HDAC6 (IC50 >100 μM). 1-Naphthohydroxamic acid does not increase global histone H4 acetylation and also does not reduce total intracellular HDAC activity[1][2], But it can induce tubulin acetylation.

Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
187.19
Formula:
C11H9NO2
Purity:
100%
Color/Form:
Solid
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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