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Gemcitabine elaidate

CAS: 210829-30-4

Ref. TM-T15378

2mg
50.00 €
5mg
97.00 €
Estimated delivery in United States, on Monday 8 Apr 2024

Product Information

Name:
Gemcitabine elaidate
Synonyms:
  • Gemcitabine 5'-elaidate, Gemcitabine (elaidate), CO-101, CP-4126
Description:

Gemcitabine elaidate (CP-4126), is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. Upon hydrolysis intracellularly by esterases, the prodrug gemcitabine is converted into the active metabolites difluorodeoxycytidine di- and tri-phosphate (dFdCDP and dFdCTP) by deoxycytidine kinase. dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA synthesis; dFdCTP is incorporated into DNA, resulting in DNA strand termination and apoptosis.

Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
527.64
Formula:
C27H43F2N3O5
MDL:
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Hazard Info

UN Number:
EQ:
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Forbidden to fly:
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Packing Group:
LQ:

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