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JNJ-10198409
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JNJ-10198409

CAS: 627518-40-5

Ref. TM-T15616

1mg
51.00 €
5mg
142.00 €
10mg
204.00 €
25mg
343.00 €
50mg
504.00 €
100mg
721.00 €
1ml*10 (DMSO)
171.00 €
Estimated delivery in United States, on Wednesday 8 May 2024

Product Information

Name:
JNJ-10198409
Synonyms:
  • JNJ10198409
  • (6,7-Dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)(3-fluorophenyl)amine
Description:

JNJ- 10198409 is a relatively selective and ATP competitive PDGF-RTK inhibitor (IC50=2 nM). JNJ-10198409 has good activity against PDGFR-β kinase (IC50=4.2 nM) and PDGFR-α kinase (IC50=45 nM). It is a dual-mechanism, antiangiogenic, and tumor cell antiproliferative agent.

Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
325.34
Formula:
C18H16FN3O2
Purity:
98.51%
Color/Form:
Solid
InChI:
InChI=1S/C18H16FN3O2/c1-23-15-7-10-6-14-17(13(10)9-16(15)24-2)21-22-18(14)20-12-5-3-4-11(19)8-12/h3-5,7-9H,6H2,1-2H3,(H2,20,21,22)
InChI key:
InChIKey=ZDNURMVOKAERHZ-UHFFFAOYSA-N
SMILES:
COc1cc2c(cc1OC)-c1[nH]nc(Nc3cccc(F)c3)c1C2
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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