Muramyl dipeptide

CAS: 53678-77-6

Ref. TM-T16159

Product Information

• Name: Muramyl dipeptide
• Synonyms: MDP, (4R)-4-{[(2S)-2-{[(2R)-2-{[(2R,3R,4R,5S,6R)-3-(acetylamino)-2,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoyl]amino}propanoyl]amino}-5-amino-5-oxopentanoic acid (non-preferred name), (4R)-4-{[(2S)-2-{[(2R)-2-{[(2R,5S)-3-(acetylamino)-2,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoyl]amino}propanoyl]amino}-5-amino-5-oxopentanoic acid (non-preferred name), 2: PN: WO2009039971 PAGE: 99 claimed protein, <span class="text-smallcaps">D</smallcap>-α-Glutamine, N-(N-acetylmuramoyl)-<smallcap>L</span>-alanyl-, <span class="text-smallcaps">D</smallcap>-α-Glutamine, N²-[N-(N-acetylmuramoyl)-<smallcap>L</span>-alanyl]-, Acetylmuramoyl-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>D</span>-isoglutamine, Acetylmuramyl-L-alanyl-D-isoglutamine, Acetylmuramyl-alanyl-isoglutamine, Brn 4220745, D-alpha-Glutamine, N(sup 2)-(N-(N-acetylmuramoyl)-L-alanyl)-, D-alpha-Glutamine, N2-(N-(N-acetylmuramoyl)-L-alanyl)-, D-α-Glutamine, N-(N-acetylmuramoyl)-L-alanyl-, D-α-Glutamine, N2-[N-(N-acetylmuramoyl)-L-alanyl]-, MDP-<span class="text-smallcaps">D</span>, Muramoyl dipeptide, N(sup 2)-(N-(N-Acetylmuramoyl)-L-alanyl)-D-alpha-glutamine, N-(Acetylmuramoyl)-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>D</span>-isoglutamine, N-(Acetylmuramoyl)alanyl-<span class="text-smallcaps">D</span>-isoglutamine, N-(Acetylmuramoyl)alanyl-D-isoglutamine, N-(N-Acetylmuramoyl)-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>D</span>-α-glutamine, N-Acetylmuramoyl dipeptide, N-Acetylmuramoyl-<span class="text-smallcaps">L</smallcap>-alanine-<smallcap>D</span>-isoGln, N-Acetylmuramoylalanyl-<span class="text-smallcaps">D</span>-isoglutamine, N-Acetylmuramyl dipeptide, N-Acetylmuramyl-L-Alanyl-D-Isoglutamine, N-Acetylmuramyl-L-alanine-D-isoGln, N2-(N-(N-Acetylmuramoyl)-L-alanyl)-D-alpha-glutamine, N2-[N-(N-Acetylmuramoyl)-L-alanyl]-D-α-glutamin, N2-[N-(N-acetilmuramoil)-L-alanil]-D-α-glutamina
• CAS: 53678-77-6

Description

Muramyl dipeptide (MDP) is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. Muramyl dipeptide indirectly decreases osteoclast differentiation through a decreased RANKL/OPG ratio. Muramyl dipeptide directly increases osteoblast differentiation by up-regulating Runx2 gene expression through MAPK pathways. Muramyl dipeptide is an inducer of bone formation through the induction of Runx2 .

• Brand: Targetmol

Chemical properties

• Molecular weight: 492.48
• Formula: C₁₉H₃₂N₄O₁₁
• Purity: 100%
• Color/Form: Solid