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PF-3450074
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PF-3450074

CAS: 1352879-65-2

Ref. TM-T16500

5mg
51.00 €
10mg
85.00 €
25mg
129.00 €
50mg
210.00 €
100mg
369.00 €
1ml*10 (DMSO)
52.00 €
Estimated delivery in United States, on Thursday 11 Apr 2024

Product Information

Name:
PF-3450074
Synonyms:
  • PF-74
Description:

PF-3450074 (PF-74) acts at an early stage of HIV-1 infection inhibits viral replication by directly competing with the binding of CPSF6 (nuclear host factors cleavage and polyadenylation specific factor 6) and NUP153 (nucleoporin 153), and blocks the uncoating, assembly, and the reverse transcription steps of the viral life cycle. PF-3450074 is a specifical inhibitor of HIV-1 capsid protein (CA) and shows a broad-spectrum inhibition of HIV isolates with submicromolar potency (EC50=8-640 nM).

Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
425.52
Formula:
C27H27N3O2
Purity:
99.92%
Color/Form:
Solid
InChI:
InChI=1S/C27H27N3O2/c1-19-23(22-15-9-10-16-24(22)28-19)18-26(31)29-25(17-20-11-5-3-6-12-20)27(32)30(2)21-13-7-4-8-14-21/h3-16,25,28H,17-18H2,1-2H3,(H,29,31)/t25-/m0/s1
InChI key:
InChIKey=ACDFWSNAQWFRRF-VWLOTQADSA-N
SMILES:
Cc1[nH]c2ccccc2c1CC(=O)N[C@@H](Cc1ccccc1)C(=O)N(C)c1ccccc1
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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