Product Information
- PROTAC Sirt-2 Degrader-1
- PROTAC Sirt2 Degrader1
PROTAC Sirt2 Degrader-1 is a SirReal-based PROTAC, acts as a Sirt2 degrader, composed of a highly potent and isotype-selective Sirt2 inhibitor, a linker, and a bona fide cereblon ligand for E3 ubiquitin ligase. PROTAC Sirt2 Degrader-1 shows an IC50 of 0.25 μM for Sirt2, with no effect on Sirt1/Sirt3 (IC50s >100 μM)[1].
Chemical properties
Technical inquiry about: TM-T16667 PROTAC Sirt2 Degrader-1
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