RG-12525
CAS: 120128-20-3
Ref. TM-T16739
2mg | 163.00 € | ||
5mg | 269.00 € | ||
10mg | 447.00 € | ||
25mg | 848.00 € | ||
50mg | 1,296.00 € | ||
1ml*10 (DMSO) | 297.00 € |
Product Information
- NID 525
- 2-[(4-{[2-(2H-tetrazol-5-ylmethyl)benzyl]oxy}phenoxy)methyl]quinoline
- 2-[[4-[[2-(2H-Tetrazol-5-ylmethyl)phenyl]methoxy]phenoxy]methyl]quinoline
- Nid 525
- Quinoline, 2-[[4-[[2-(1H-tetrazol-5-ylmethyl)phenyl]methoxy]phenoxy]methyl]-
- Quinoline, 2-[[4-[[2-(2H-tetrazol-5-ylmethyl)phenyl]methoxy]phenoxy]methyl]-
- Rg-12525
RG-12525(NID 525) is an orally available, selective and competitive leukotriene D (LTD) antagonist that inhibits LTC4, LTD4 and LTE4-induced contraction of guinea pig thin-walled bands, with IC50 values of 2.6 nM, 2.5 nM, and 7 nM, respectively.RG-12525 inhibits CYP3A4, with a Ki value of 0.5 µM. RG-12525 is a novel and potent PPAR-γ agonist (IC50 value of about 60 nM) with species specificity for the study of asthma.
Chemical properties
Technical inquiry about: TM-T16739 RG-12525
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