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Ceritinib dihydrochloride
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Ceritinib dihydrochloride

CAS: 1380575-43-8

Ref. TM-T1791L

5mg
50.00 €
10mg
63.00 €
25mg
76.00 €
50mg
92.00 €
100mg
122.00 €
1ml*10 (DMSO)
65.00 €
Estimated delivery in United States, on Thursday 18 Apr 2024

Product Information

Name:
Ceritinib dihydrochloride
Synonyms:
  • LDK378 dihydrochloride
  • 5-chloro-2-N-(5-methyl-4-piperidin-4-yl-2-propan-2-yloxyphenyl)-4-N-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine,dihydrochloride
  • Cs-1407
  • W-6134
  • LDK-378 dihydrochloride
  • 5-Chloro-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine hydrochloride
  • 5-Chloro-N2-(2-Isopropoxy-5-Methyl-4-(Piperidin-4-Yl)Phenyl)-N4-(2-(Isopropylsulfonyl)Phenyl)Pyrimidine-2,4-Diamine 2Hcl
  • LDK378 2Hcl
  • 5-chloro-N2-(2-isopropoxy-5-Methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyriMidine-2,4-diaMine hydrochloride
  • 5-Chloro-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine hydrochloride (1:2)
  • See more synonyms
Description:

Ceritinib dihydrochloride (LDK378 dihydrochloride) is a selective, orally bioavailable and ATP-competitive inhibitor of ALK tyrosine kinase(IC50 of 200 pM), and also inhibits IGF-1R, InsR, and STK22D (IC50 values of 8, 7, and 23 nM, respectively), shows great antitumor potency

Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
631.06
Formula:
C28H38Cl3N5O3S
Purity:
99.99%
Color/Form:
Solid
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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