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Momelotinib
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Momelotinib

CAS: 1056634-68-4

Ref. TM-T1849

1mg
38.00 €
2mg
49.00 €
5mg
80.00 €
10mg
93.00 €
25mg
163.00 €
50mg
254.00 €
100mg
399.00 €
200mg
612.00 €
1ml*10 (DMSO)
88.00 €
Estimated delivery in United States, on Thursday 18 Apr 2024

Product Information

Name:
Momelotinib
Synonyms:
  • CYT11387, CYT387, LM-1149
  • Benzamide, N-(cyanomethyl)-4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]-
  • CYT 387 mesylate
  • Cyt 11387
  • Cyt-0387
  • Cyt387
  • Gs 0387
  • N-(Cyanomethyl)-4-[2-(4-morpholinoanilino)pyrimidin-4-yl]benzamide
  • N-(Cyanomethyl)-4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]benzamide
Description:

Momelotinib (LM-1149) is an orally bioavailable small-molecule inhibitor of Janus kinases 1 and 2 (JAK1/2) with IC50 of 11 nM/18 nM. JAK1/2 inhibitor CYT387 competes with JAK1/2 for ATP binding, which may result in inhibition of JAK1/2 activation, inhibition of the JAK-STAT signaling pathway, and so the induction of apoptosis and a reduction of tumor cell proliferation in JAK1/2-expressing tumor cells.

Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
414.46
Formula:
C23H22N6O2
Purity:
99.56%
Color/Form:
Solid
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

Technical inquiry about: TM-T1849 Momelotinib

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