Zaprinast

CAS: 37762-06-4

Ref. TM-T2129

Product Information

• Name: Zaprinast
• Synonyms: 1,4-Dihydro-5-(2-propoxyphenyl)-1,2,3-triazolo(4,5-d)pyrimidin-7-one, 2-(2-Propoxyphenyl)-8-aza-6-purinone, 2-(o-Propoxyphenyl)-8-azapurin-6-one, 2-o-Propoxyphenyl-8-azapurin-6-on, 2-o-Propoxyphenyl-8-azapurine-6-one, 3,6-Dihydro-5-(2-propoxyphenyl)-7H-(1,2,3)truaziki(4,5-d)pyrimidin-7-on, 3,6-Dihydro-5-(2-propoxyphenyl)-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one, 3,6-Dihydro-5-(o-propoxyphenyl)-7H-v-triazolo(4,5-d)pyrimidin-7-one, 5-(2-Propoxyphenyl)-1H-[1,2,3]triazolo[4,5-d]pyrimidin-7(4H)-one, 5-(2-propoxyphenyl)-2,3-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one, 6,7-Dihydro-5-(2-propoxyphenyl)-1H-triazolo(4,5-d)pyrimidin-7-on, 6,7-Dihydro-5-(2-propoxyphenyl)-1H-triazolo(4,5-d)pyrimidin-7-on [IUPAC], 7H-1,2,3-Triazolo(4,5-d)pyrimidin-7-one, 1,4-dihydro-5-(2-propoxyphenyl)-, 7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one, 3,6-dihydro-5-(2-propoxyphenyl)-, 8-Aza-2-(2-propoxyphenyl)-6-purinone, M and B 22948, M&B 22,948, Unii-Gxt25D5Ds0, Zaprinast [INN:BAN], Zaprinastum, Zaprinastum [INN-Latin]
• CAS: 37762-06-4

Description

Zaprinast is a cGMP-selective phosphodiesterase (PDE) inhibitor and a GPR35 agonist. It has a strong activating effect on rat GPR35 and a certain activating effect on human GPR35. It reduces vascular remodeling through anti-proliferative and pro-apoptotic effects.

• Brand: Targetmol

Chemical properties

• Molecular weight: 271.27
• Formula: C₁₃H₁₃N₅O₂
• Purity: 99.73%
• Color/Form: White To Off White Powder