Bimiralisib
CAS: 1225037-39-7
Ref. TM-T2265
| 1mg | 42.00 € | ||
| 2mg | 56.00 € | ||
| 5mg | 89.00 € | ||
| 10mg | 120.00 € | ||
| 25mg | 216.00 € | ||
| 50mg | 364.00 € | ||
| 100mg | 548.00 € | ||
| 500mg | 1,194.00 € |
Estimated delivery in United States, on Wednesday 15 May 2024
Product Information
Name:
Bimiralisib
Synonyms:
- 5-(4,6-dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine, PQR309, PI3K-IN-2
CAS:
Description:
Bimiralisib (PI3K-IN-2) is an orally bioavailable pan inhibitor of PI3K and inhibitor of the mTOR, with potential antineoplastic activity. PI3K-IN-2 inhibits the PI3K kinase isoforms alpha, beta, gamma and delta and, to a lesser extent, mTOR kinase, which may result in tumor cell apoptosis and growth inhibition in cells overexpressing PI3K/mTOR. Activation of the PI3K/mTOR pathway promotes cell growth, survival, and resistance to both chemotherapy and radiotherapy.
Brand:
Targetmol
Long term storage:
Notes:
Chemical properties
Molecular weight:
411.38
Formula:
C17H20F3N7O2
Purity:
99.88%
Color/Form:
Solid
InChI:
InChI=1S/C17H20F3N7O2/c18-17(19,20)12-9-13(21)22-10-11(12)14-23-15(26-1-5-28-6-2-26)25-16(24-14)27-3-7-29-8-4-27/h9-10H,1-8H2,(H2,21,22)
InChI key:
InChIKey=ADGGYDAFIHSYFI-UHFFFAOYSA-N
SMILES:
Nc1cc(C(F)(F)F)c(-c2nc(N3CCOCC3)nc(N3CCOCC3)n2)cn1
MDL:
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