PX-12
CAS: 141400-58-0
Ref. TM-T2283
5mg | 51.00 € | ||
10mg | 73.00 € | ||
25mg | 129.00 € | ||
50mg | 231.00 € | ||
100mg | 385.00 € | ||
500mg | 881.00 € | ||
1ml*10 (DMSO) | 56.00 € |
Product Information
- IV-2, PX12
- MID
- Iv-2
- Px-12
- 2-(butan-2-yldisulfanyl)-1H-imidazole
PX-12 (PX12) (1-methylpropyl 2-imidazolyl disulfide) is a small-molecule inhibitor of Trx-1 (thioredoxin-1), stimulates apoptosis, down-regulates HIF-1α and vascular endothelial growth factor (VEGF) and inhibits tumor growth in animal models. Since high levels of Trx-1 have been associated with colorectal, gastric and lung cancers, PX-12 is indicated as a potential cancer treatment in combination with chemotherapy for patients with advanced metastatic cancer. Initial trials correlated doses of Px-12 with increased patient survival.
Chemical properties
Technical inquiry about: TM-T2283 PX-12
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