MK-571 sodium
CAS: 115103-85-0
Ref. TM-T3148
| 5mg | 51.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 295.00 € | ||
| 100mg | 440.00 € | ||
| 1ml*10 (DMSO) | 68.00 € |
Product Information
- L-660711 (sodium salt), L-660711 sodium salt, Verlukast sodium, L-660711, MK571, MK-571 sodium salt, Propanoic acid
MK-571 sodium (L-660711 sodium salt) is a selective, orally active antagonist of the CysLT1 receptor. MK-571 sodium is a multidrug resistance protein-2 (ABCC2, Mrp2) inhibitor used to demonstrate the role of Mrp2 in the cellular efflux of drugs, xenobiotics, and their conjugates. MK-571 sodium can inhibit the synthesis of K-4′-O-GlcA (19.7 μM). MK571 dose-dependently inhibits the intracellular biosynthesis of all flavonol sulphates and glucuronides by Caco-2 cells. MK-571 sodium significantly inhibits phase-2 conjugation of kaempferol by cell-free extracts of Caco-2, and production of kaempferol-4′-O-glucuronide was competitively inhibited. In addition to inhibiting MRP2, MK571 is a potent inhibitor of enterocyte phase-2 conjugation.
Chemical properties
Technical inquiry about: TM-T3148 MK-571 sodium
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