Senicapoc
CAS: 289656-45-7
Ref. TM-T3528
5mg | 58.00 € | ||
10mg | 94.00 € | ||
25mg | 130.00 € | ||
50mg | 170.00 € | ||
100mg | 220.00 € | ||
200mg | 328.00 € | ||
1ml*10 (DMSO) | 70.00 € |
Product Information
- ICA-17043
- 4-Fluoro-α-(4-fluorophenyl)-α-phenylbenzeneacetamide
- Benzeneacetamide, 4-fluoro-α-(4-fluorophenyl)-α-phenyl-
- Ica-17043
Senicapoc (ICA-17043) is a potent inhibitor of the Gardos channel and ameliorates RBC dehydration in the SAD mouse. Senicapoc blocked Ca2+-induced rubidium flux from human RBCs with an IC50 value of 11 ± 2 nM (CLT IC50 = 100 ± 12 nM) and inhibited RBC dehydration with an IC50 of 30 ± 20 nM. Senicapoc is in treatment of Sickle Cell Disease and Sickle Cell Anemia
Chemical properties
Technical inquiry about: TM-T3528 Senicapoc
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