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Senicapoc
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Senicapoc

CAS: 289656-45-7

Ref. TM-T3528

5mg
58.00 €
10mg
94.00 €
25mg
130.00 €
50mg
170.00 €
100mg
220.00 €
200mg
328.00 €
1ml*10 (DMSO)
70.00 €
Estimated delivery in United States, on Thursday 18 Apr 2024

Product Information

Name:
Senicapoc
Synonyms:
  • ICA-17043
  • 4-Fluoro-α-(4-fluorophenyl)-α-phenylbenzeneacetamide
  • Benzeneacetamide, 4-fluoro-α-(4-fluorophenyl)-α-phenyl-
  • Ica-17043
Description:

Senicapoc (ICA-17043) is a potent inhibitor of the Gardos channel and ameliorates RBC dehydration in the SAD mouse. Senicapoc blocked Ca2+-induced rubidium flux from human RBCs with an IC50 value of 11 ± 2 nM (CLT IC50 = 100 ± 12 nM) and inhibited RBC dehydration with an IC50 of 30 ± 20 nM. Senicapoc is in treatment of Sickle Cell Disease and Sickle Cell Anemia

Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
323.34
Formula:
C20H15F2NO
Purity:
99.5%
Color/Form:
Solid
InChI:
InChI=1S/C20H15F2NO/c21-17-10-6-15(7-11-17)20(19(23)24,14-4-2-1-3-5-14)16-8-12-18(22)13-9-16/h1-13H,(H2,23,24)
InChI key:
InChIKey=SCTZUZTYRMOMKT-UHFFFAOYSA-N
SMILES:
NC(=O)C(c1ccccc1)(c1ccc(F)cc1)c1ccc(F)cc1
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

Technical inquiry about: TM-T3528 Senicapoc

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